Colchicine for the prevention of postoperative atrial fibrillation: a new indication for a very old drug?
نویسنده
چکیده
Arrhythmia/Electrophysiology Colchicine Reduces Postoperative Atrial Fibrillation: Results of the Colchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) Atrial Fibrillation Substudy Massimo Imazio, MD; Antonio Brucato, MD; Paolo Ferrazzi, MD; Maria Elena Rovere, MD; Anna Gandino, MD; Roberto Cemin, MD; Stefania Ferrua, MD; Riccardo Belli, MD; Silvia Maestroni, MD; Caterina Simon, MD; Edoardo Zingarelli, MD; Alberto Barosi, MD; Fabrizio Sansone, MD; Davide Patrini, MD; Ettore Vitali, MD; Rita Trinchero, MD; David H. Spodick, MD; Yehuda Adler, MD; for the COPPS Investigators Clinical Perspective ➡2290
منابع مشابه
بررسی تأثیر کلشیسین خوراکی با دوز کم در کاهش بروز فیبریلاسیون دهلیزی پس از عمل جراحی بایپس کرونری: کارآزمایی بالینی تصادفی دوسوکور
Background: The occurrence of Atrial Fibrillation (AF) is linked to an increased inflam-matory response after cardiac surgery that is significantly decreased by anti-inflammatory treatments. The present study aimed at administrating Colchicine as a way to reduce the incidence of post- Coronary Artery Bypass Graft (CABG) atrial fibrillation. Methods: In this double-blind, parallel clinical tria...
متن کاملColchicine for the Prevention of Postoperative Atrial Fibrillation A New Indication for a Very Old Drug?
Atrial fibrillation after cardiac surgery (postoperative atrial fibrillation [POAF]) is a common problem, affecting 10% to 50% of all cardiac surgery patients, with the risks of POAF increasing as a function of patient age and the complexity of the surgery performed. POAF is associated with increased length of hospital stay, increased risk of comorbid conditions, and increased risk of mortality...
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Background: Atrial fibrillation is the most common arrhythmia after cardiac surgery. Vitamin C as an antioxidant has an important role in reducing the incidence of postop-erative atrial fibrillation. The present study aimed at administrating vitamin C as a way to reduce the incidence of post-CABG atrial fibrillation. Methods: In this double-blind, parallel clinical trial, 170 patients with cor...
متن کاملاسید آسکوربیک خوراکی به همراه بتا بلوکرها روشی موثر برای کاهش فیبریلاسیون دهلیزی به دنبال عمل جراحی بای پس عروق کرونر
Background: Adrenergic beta antagonists are not sufficient to prevent atrial fibrillation after coronary artery bypass graft (CABG). This study was designed to evaluate the effect of ascorbic acid as an adjunct to beta-blockers in prevention of post-CABG atrial fibrillation Methods: Patients who were more than 50 years old and scheduled to undergo CABG were included if they were treated with b...
متن کاملArrhythmia/Electrophysiology Colchicine Reduces Postoperative Atrial Fibrillation Results of the Colchicine for the Prevention of the Postpericardiotomy Syndrome (COPPS) Atrial Fibrillation Substudy
Background—Inflammation and pericarditis may be contributing factors for postoperative atrial fibrillation (POAF), and both are potentially affected by antiinflammatory drugs and colchicine, which has been shown to be safe and efficacious for the prevention of pericarditis and the postpericardiotomy syndrome (PPS). The aim of the Colchicine for the Prevention of the Post-Pericardiotomy Syndrome...
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ورودعنوان ژورنال:
- Circulation
دوره 124 21 شماره
صفحات -
تاریخ انتشار 2011